Senior Infrastructure Engineer
Top Benefits
About the role
Success Profile
What makes a successful Senior Infrastructure Engineer? Here are the top traits.
Conceptual
Proactive
Problem-Solver
Strategic
Technologically Savvy
Visual Thinker
Culture
Accomplish
Make a meaningful impact by using your problem-solving skills to push the boundaries of innovation in healthcare, while maintaining a healthy work-life balance.
Innovate
Foster a digital mindset to drive IT transformation across McKesson through our evolving data and technology tools.
Grow
Join a supportive environment where you can advance your career and develop both personally and professionally.
Benefits
Coverage you can rely on
- Medical, Dental, and Vision
- Health Spending Accounts
- Flexible Spending Accounts
Benefits that go beyond your base pay
- 401(k) (U.S.)
- Pension (Canada)
- Employee Stock Purchase Plan
Support for total well-being
- Mental Health Programs
- Flexible Schedules
- Paid Time Off
- Wellness Program
- Education Reimbursement
- Volunteer Opportunities
- Flexible Work Environment
A culture powered by belonging
By fostering a culture of belonging, we advance our goal of being the best place to work in healthcare—connecting the right talent to the right roles to solve our most critical challenges.
Responsibility
McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.
What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
The Senior Infrastructure Engineer is responsible for planning, designing, and executing enterprise infrastructure modernization initiatives, including large‑scale migrations from legacy on‑premises environments to Azure Local and hybrid Azure cloud platforms. This role works in close partnership with engineering, architecture, application, operations, and cybersecurity teams to deliver secure, scalable, and resilient infrastructure solutions.
The ideal candidate brings deep hands‑on technical expertise across VMware, Microsoft Azure, Azure Local, core server platforms, and automation, with a proven track record of delivering complex data center and enterprise migrations that achieve measurable improvements in performance, reliability, scalability, and cost optimization.
This role requires strong engineering judgment, the ability to execute technically complex work end‑to‑end, and comfort operating in highly regulated, large‑scale enterprise environments.
The Senior Infrastructure Engineer plays a critical role in modernizing McKesson’s infrastructure, accelerating cloud adoption, improving platform reliability, reducing technical debt, and delivering tangible business value across the organization.
Infrastructure Strategy & Design:
- Plan, design, and implement migration initiatives across on‑premises, hybrid, and Azure cloud environments.
- Architect scalable, resilient, and secure infrastructure solutions aligned with McKesson enterprise standards.
- Evaluate legacy infrastructure and define modernization and migration strategies that support business objectives.
Migration Execution & Delivery:
- Deliver migration plans that achieve documented performance improvements, availability enhancements, or cost savings.
- Lead the planning and execution of large-scale server and data center migrations to Azure Local and hybrid cloud environments, ensuring stability, performance, and minimal operational disruption.
- Partner with application teams to align infrastructure migrations with application architecture and deployment processes.
Automation, Governance & Operational Excellence:
- Leverage Infrastructure as Code (IaC) tools with Terraform or Ansible to deliver scalable, repeatable, and governance-aligned compute environments that support enterprise reliability and compliance.
- Maintain accurate and up-to-date system documentation across on-premises, hybrid, and cloud platforms, including the creation, maintenance, and retirement (purging) of Configuration Management Database (CMDB) records, ensuring infrastructure assets, configuration items, and dependencies are properly documented to support operational integrity, lifecycle management, and audit readiness.
- Utilize and adhere to the McKesson Change Management process to plan, review, and implement changes within production and disaster recovery environments, ensuring minimal disruption and controlled risk.
- Participate in change reviews, implementation planning, and post‑implementation validation to confirm changes meet technical, operational, and business requirements.
Operational Readiness & Cross-Team Collaboration:
- Ensure infrastructure solutions comply with McKesson cybersecurity, compliance, and operational policies.
- Collaborate with compute, network, storage, operations, and cybersecurity teams to ensure end‑to‑end solution integrity and operational readiness.
- Act as a post-migration escalation point for complex infrastructure issues, providing root cause analysis and remediation, while serving as a trusted technical advisor who clearly communicates recommendations, outcomes, and risks to both technical and non-technical stakeholders.
Section B – General Responsibilities
- Seek to provide candid and timely feedback to improve performance; openly share information; foster teamwork and innovation by involving team members in problem-solving, decision-making, and creative thinking.
- Ensure that requirements to internal and external customers are met in a timely and cost-effective manner; solicit feedback from customers to identify opportunities to improve products and/or services; resolve minor conflicts and involve team members in problem resolution.
- decision-making authority and autonomy needed to deliver accountabilities of job/role; seek approval from others on matters outside of job/role scope; when required, make decisions regarding the work and development of project team members.
- Build internal and external relationships with key suppliers, customers, and internal service providers, with an emphasis on facilitating successful job/role responsibilities.
- Respect and adhere to McKesson Standards, Policies, and Procedures.
- Meet job performance standards and objectives outlined in the progress and appraisal guidelines.
Section C – Position Requirements
Minimum Qualifications :-
- 8+ years of hands‑on experience in enterprise infrastructure or systems engineering roles supporting large‑scale, business‑critical environments and Bachelor’s degree in Computer Science, Computer Engineering, or a related discipline, or equivalent hands‑on industry experience.
Knowledge:
- expertise in enterprise operating systems, Microsoft Azure, VMware, and enterprise storage platforms, with strong experience designing, building, operating, and troubleshooting hybrid architectures across on-premises and Azure environments.
- Proven track record of executing large‑scale server and workload migrations from on‑premises environments to hybrid and public cloud platforms.
- Advanced proficiency in PowerShell scripting to automate infrastructure provisioning, configuration, migration activities, and ongoing operational tasks.
- Strong working knowledge of application architecture and deployment processes, with the ability to align infrastructure design and implementation to application and business requirements.
Ability to:
- Lead complex infrastructure modernization and migration initiatives, driving technical execution from design through implementation across on‑premises, Azure Local, and hybrid Azure environments.
- strong engineering judgment to plan, build, and implement infrastructure solutions that meet enterprise requirements for security, reliability, performance, and compliance.
- Anticipate and manage technical risks and dependencies throughout infrastructure and migration projects, ensuring stable implementations with minimal operational disruption.
- Serve as a post‑implementation escalation point to analyze, troubleshoot, and remediate infrastructure issues when required, ensuring long‑term solution stability and resilience.
- Operate with a high degree of ownership and accountability, independently prioritizing work, managing deliverables, and executing within defined project timelines and change windows.
- Collaborate effectively with engineering, architecture, application, operations, and cybersecurity teams to deliver end‑to‑end infrastructure solutions aligned with McKesson standards.
- Demonstrate clear and effective written and verbal communication skills in English, with the ability to articulate technical designs, risks, implementation outcomes, and recommendations to both technical and non‑technical stakeholders.
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson,
(opens in new window)
Our Base Pay Range for this position
$99,100 - $132,100
McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
McKesson job postings are posted on our career site: careers.mckesson.com
(opens in new window)
.
McKesson is an Equal Opportunity Employer
McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity
(opens in new window)
page.
McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com
(opens in new window)
or (Canada) Accessibility@mckesson.ca
(opens in new window)
. Resumes or CVs submitted to this email box will not be accepted.
Join us at McKesson!
Not the right fit? Search for Infrastructure Engineer jobs in Mississauga, ON
About McKesson
Welcome to the official LinkedIn page for McKesson Corporation. We're an impact-driven healthcare organization dedicated to “Advancing Health Outcomes For All.”
As a global healthcare company, we touch virtually every aspect of health. Our leaders empower our people to lead with a growth mindset and deliver excellence for our customers, partners, and the wellbeing of people, everywhere. We work with biopharma companies, care providers, pharmacies, manufacturers, governments, and others to deliver insights, products and services that make quality care more accessible and affordable. Delivering better health outcomes for our employees, our communities, and our environment. Every day, we strive to inspire and enable people to reach their full potential.
To learn more about how #TeamMckesson helps improve care in every setting, visit: https://bit.ly/3xadvB0
Similar Jobs
Senior Infrastructure Engineer
Top Benefits
About the role
Success Profile
What makes a successful Senior Infrastructure Engineer? Here are the top traits.
Conceptual
Proactive
Problem-Solver
Strategic
Technologically Savvy
Visual Thinker
Culture
Accomplish
Make a meaningful impact by using your problem-solving skills to push the boundaries of innovation in healthcare, while maintaining a healthy work-life balance.
Innovate
Foster a digital mindset to drive IT transformation across McKesson through our evolving data and technology tools.
Grow
Join a supportive environment where you can advance your career and develop both personally and professionally.
Benefits
Coverage you can rely on
- Medical, Dental, and Vision
- Health Spending Accounts
- Flexible Spending Accounts
Benefits that go beyond your base pay
- 401(k) (U.S.)
- Pension (Canada)
- Employee Stock Purchase Plan
Support for total well-being
- Mental Health Programs
- Flexible Schedules
- Paid Time Off
- Wellness Program
- Education Reimbursement
- Volunteer Opportunities
- Flexible Work Environment
A culture powered by belonging
By fostering a culture of belonging, we advance our goal of being the best place to work in healthcare—connecting the right talent to the right roles to solve our most critical challenges.
Responsibility
McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.
What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
The Senior Infrastructure Engineer is responsible for planning, designing, and executing enterprise infrastructure modernization initiatives, including large‑scale migrations from legacy on‑premises environments to Azure Local and hybrid Azure cloud platforms. This role works in close partnership with engineering, architecture, application, operations, and cybersecurity teams to deliver secure, scalable, and resilient infrastructure solutions.
The ideal candidate brings deep hands‑on technical expertise across VMware, Microsoft Azure, Azure Local, core server platforms, and automation, with a proven track record of delivering complex data center and enterprise migrations that achieve measurable improvements in performance, reliability, scalability, and cost optimization.
This role requires strong engineering judgment, the ability to execute technically complex work end‑to‑end, and comfort operating in highly regulated, large‑scale enterprise environments.
The Senior Infrastructure Engineer plays a critical role in modernizing McKesson’s infrastructure, accelerating cloud adoption, improving platform reliability, reducing technical debt, and delivering tangible business value across the organization.
Infrastructure Strategy & Design:
- Plan, design, and implement migration initiatives across on‑premises, hybrid, and Azure cloud environments.
- Architect scalable, resilient, and secure infrastructure solutions aligned with McKesson enterprise standards.
- Evaluate legacy infrastructure and define modernization and migration strategies that support business objectives.
Migration Execution & Delivery:
- Deliver migration plans that achieve documented performance improvements, availability enhancements, or cost savings.
- Lead the planning and execution of large-scale server and data center migrations to Azure Local and hybrid cloud environments, ensuring stability, performance, and minimal operational disruption.
- Partner with application teams to align infrastructure migrations with application architecture and deployment processes.
Automation, Governance & Operational Excellence:
- Leverage Infrastructure as Code (IaC) tools with Terraform or Ansible to deliver scalable, repeatable, and governance-aligned compute environments that support enterprise reliability and compliance.
- Maintain accurate and up-to-date system documentation across on-premises, hybrid, and cloud platforms, including the creation, maintenance, and retirement (purging) of Configuration Management Database (CMDB) records, ensuring infrastructure assets, configuration items, and dependencies are properly documented to support operational integrity, lifecycle management, and audit readiness.
- Utilize and adhere to the McKesson Change Management process to plan, review, and implement changes within production and disaster recovery environments, ensuring minimal disruption and controlled risk.
- Participate in change reviews, implementation planning, and post‑implementation validation to confirm changes meet technical, operational, and business requirements.
Operational Readiness & Cross-Team Collaboration:
- Ensure infrastructure solutions comply with McKesson cybersecurity, compliance, and operational policies.
- Collaborate with compute, network, storage, operations, and cybersecurity teams to ensure end‑to‑end solution integrity and operational readiness.
- Act as a post-migration escalation point for complex infrastructure issues, providing root cause analysis and remediation, while serving as a trusted technical advisor who clearly communicates recommendations, outcomes, and risks to both technical and non-technical stakeholders.
Section B – General Responsibilities
- Seek to provide candid and timely feedback to improve performance; openly share information; foster teamwork and innovation by involving team members in problem-solving, decision-making, and creative thinking.
- Ensure that requirements to internal and external customers are met in a timely and cost-effective manner; solicit feedback from customers to identify opportunities to improve products and/or services; resolve minor conflicts and involve team members in problem resolution.
- decision-making authority and autonomy needed to deliver accountabilities of job/role; seek approval from others on matters outside of job/role scope; when required, make decisions regarding the work and development of project team members.
- Build internal and external relationships with key suppliers, customers, and internal service providers, with an emphasis on facilitating successful job/role responsibilities.
- Respect and adhere to McKesson Standards, Policies, and Procedures.
- Meet job performance standards and objectives outlined in the progress and appraisal guidelines.
Section C – Position Requirements
Minimum Qualifications :-
- 8+ years of hands‑on experience in enterprise infrastructure or systems engineering roles supporting large‑scale, business‑critical environments and Bachelor’s degree in Computer Science, Computer Engineering, or a related discipline, or equivalent hands‑on industry experience.
Knowledge:
- expertise in enterprise operating systems, Microsoft Azure, VMware, and enterprise storage platforms, with strong experience designing, building, operating, and troubleshooting hybrid architectures across on-premises and Azure environments.
- Proven track record of executing large‑scale server and workload migrations from on‑premises environments to hybrid and public cloud platforms.
- Advanced proficiency in PowerShell scripting to automate infrastructure provisioning, configuration, migration activities, and ongoing operational tasks.
- Strong working knowledge of application architecture and deployment processes, with the ability to align infrastructure design and implementation to application and business requirements.
Ability to:
- Lead complex infrastructure modernization and migration initiatives, driving technical execution from design through implementation across on‑premises, Azure Local, and hybrid Azure environments.
- strong engineering judgment to plan, build, and implement infrastructure solutions that meet enterprise requirements for security, reliability, performance, and compliance.
- Anticipate and manage technical risks and dependencies throughout infrastructure and migration projects, ensuring stable implementations with minimal operational disruption.
- Serve as a post‑implementation escalation point to analyze, troubleshoot, and remediate infrastructure issues when required, ensuring long‑term solution stability and resilience.
- Operate with a high degree of ownership and accountability, independently prioritizing work, managing deliverables, and executing within defined project timelines and change windows.
- Collaborate effectively with engineering, architecture, application, operations, and cybersecurity teams to deliver end‑to‑end infrastructure solutions aligned with McKesson standards.
- Demonstrate clear and effective written and verbal communication skills in English, with the ability to articulate technical designs, risks, implementation outcomes, and recommendations to both technical and non‑technical stakeholders.
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson,
(opens in new window)
Our Base Pay Range for this position
$99,100 - $132,100
McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
McKesson job postings are posted on our career site: careers.mckesson.com
(opens in new window)
.
McKesson is an Equal Opportunity Employer
McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity
(opens in new window)
page.
McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com
(opens in new window)
or (Canada) Accessibility@mckesson.ca
(opens in new window)
. Resumes or CVs submitted to this email box will not be accepted.
Join us at McKesson!
Not the right fit? Search for Infrastructure Engineer jobs in Mississauga, ON
About McKesson
Welcome to the official LinkedIn page for McKesson Corporation. We're an impact-driven healthcare organization dedicated to “Advancing Health Outcomes For All.”
As a global healthcare company, we touch virtually every aspect of health. Our leaders empower our people to lead with a growth mindset and deliver excellence for our customers, partners, and the wellbeing of people, everywhere. We work with biopharma companies, care providers, pharmacies, manufacturers, governments, and others to deliver insights, products and services that make quality care more accessible and affordable. Delivering better health outcomes for our employees, our communities, and our environment. Every day, we strive to inspire and enable people to reach their full potential.
To learn more about how #TeamMckesson helps improve care in every setting, visit: https://bit.ly/3xadvB0