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Research Fellow - Wound Healing

Toronto, Ontario
Mid Level
full_time

About the role

Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world. As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education. Our reputation would not have been built - nor could it be maintained - without the skills, knowledge and experience of the extraordinary people who come to work here every day. SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.

When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World .

Don't miss out on the opportunity to work alongside the world's best in paediatric healthcare.

Interdisciplinary Post-Doctoral Fellowships (2 positions) in Wound Healing SickKids Research Institute, Toronto, Canada and University of Montpellier, Montpellier, France The Zhulyn and Lagha labs are jointly seeking two talented postdoctoral fellows for a collaborative team project to uncover the cellular 'band aid' proteins that enable rapid wound healing in axolotls and flies.

Funded by the prestigious Human Frontier Science Foundation Program research grant, this project brings together complementary expertise of the Zhulyn (Canada), Lagha (France), vanOudenaarden (Netherlands) and Kelleher (US) labs for a team-driven, multidisciplinary effort to identify and visualize the translation dynamics and function of proteins that drive epithelial cell migration and rapid, scarless wound healing in axolotl wound healing and fly dorsal closure.

All Applicants Must Have a Successful applicants will work together as part of an international team of experts at four sites to apply cutting-edge approaches in high-resolution, single-molecule imaging; single-cell Ribo-seq and spatial mass spectrometry. They will also design and implement new tools for visualization of mRNA translation at a global and single-molecule level and develop a new framework for mRNA translation and protein analysis at unprecedented resolution in axolotls and flies. The positions require both overlapping and distinct skill sets as outlined below:

  • Ph.D. in Molecular Biology, Genetics, Cell Biology, Biophysics or a related field
  • Competency in computational (R or Python) and statistical analysis
  • Competency in experimental design and standard molecular biology, imaging, genetics techniques
  • Demonstrated manual dexterity, precision, and rigor in experimental work
  • Driven to learn and innovate and work both independently and as part of a team
  • Minimum of one first-author publication in a peer-reviewed journal
  • Fluent in English (native or bilingual proficiency)

In Addition Applicants to the Zhulyn lab (Canada) must have:

  • Experience with confocal or high-resolution imaging in live or fixed organisms, cells or tissues
  • Experience with data analysis in Python, R or similar
  • Experience working with animal models
  • Experience with mass spectrometry, including sample preparation and data analysis

AND/OR

  • Experience with scRNA-Seq, CHIP-Seq or related methods, including library preparation and data analysis

AND/OR

  • Extensive experience with in vitro or in vitro reporter assay design, development and implementation

Applicants To The Lagha Lab (France) Must Have

  • Experience with high-resolution or live imaging in flies, zebrafish or other animal model, organoid or related systems
  • Experience in Drosophila genetics would be a strong asset
  • Knowledge in developmental, cell or regenerative biology

About The Institutions The Zhulyn lab is located in the Peter Gilgan Centre for Research and Learning (PGCRL). A state-of-the-art research tower housing the SickKids Research Institute of the Hospital for Sick Children - a global leader in pediatric medicine and research.

PGCRL is situated in the heart of downtown Toronto's 'Hospital Row' which features one of the world's highest densities of clinical and research talent with over 11,000 researchers spread across 9 hospitals, 37 research institutes in one of the most productive academic health centers in North America.

The Lagha lab is located in the Institut de Génétique Moléculaire de Montpellier (IGMM) in the historic CNRS Montpellier "Route de Mende" campus. It is physically connected to CRBM and IRIM research institutes, forming a critical mass of 600 people who create an exceptional dynamic intellectual and technological environment. The labs at IGMM have access to high-tech facilities, through BioCampus.

In addition, successful applicants will have opportunities to travel and work closely with our team members at the Hubrecht Institute (Netherlands) and Northwestern University (United States).

Qualified applicants are invited to submit an application to SickKids OR IGMM [via e-mail to:mounia.lagha@igmm.cnrs.fr with "HFSP Post doc application" in the subject line]. Applicants wishing to apply to both labs may submit a single application to either institute and indicate ('for dual consideration') in their cover letter.

The Application Must Include- Curriculum vitae with the applicant's publication record and contact information of 3 referees.

  • Cover letter describing your interest in the position Brief description of previous research (<1 page)

Position start date is on or after December 2025. The appointment is for 3 years with possibility of extension depending on funding and performance. Salary is competitive and in accord with CNRS and SickKids Research Institute standards.

SickKids is committed to championing equity, diversity and inclusion in all that we do, fostering an intentionally inclusive and culturally safe environment that reflects the diversity of the patients, families and communities we serve. Learn more about workplace inclusion.

If you require accommodation during the application process, please reach out to our aSKHR team. SickKids can provide access and inclusion supports to eligible candidates to support their full engagement during the interview and selection process as well as to ensure candidates are able to perform their duties once successfully hired. If you are invited for an interview and require accommodation, please let us know at the time of your invitation to interview. Information received related to access, inclusion or accommodation will be addressed confidentially.

Technical difficulties? Email ask.hr@sickkids.ca with a short description of the issues you are experiencing. We will not accept resumes sent to this inbox but we are happy to respond to requests for technical assistance.

Tip: Combine your cover letter and resume into ONE document of 20 pages or less as you cannot upload multiple documents as part of your application.

About The Hospital for Sick Children

Hospitals and Health Care
5001-10,000

The Hospital for Sick Children (SickKids) is recognized as one of the world’s foremost paediatric health-care institutions and is Canada’s leading centre dedicated to advancing children’s health through the integration of patient care, research and education. Founded in 1875 and affiliated with the University of Toronto, SickKids is one of Canada’s most research-intensive hospitals and has generated discoveries that have helped children globally.

Its mission is to provide the best in complex and specialized family-centred care; pioneer scientific and clinical advancements; share expertise; foster an academic environment that nurtures health-care professionals; and champion an accessible, comprehensive and sustainable child health system.

SickKids is a founding member of Kids Health Alliance, a network of partners working to create a high quality, consistent and coordinated approach to paediatric health care that is centred around children, youth and their families.

SickKids is proud of its vision of Healthier Children. A Better World.™