Portfolio Manager - MES & Digital Manufacturing
Top Benefits
About the role
At NTT DATA, we know that with the right people on board, anything is possible. The quality, integrity, and commitment of our employees have been key factors in our company's growth and market presence. By hiring the best people and helping them grow both professionally and personally, we ensure a bright future for NTT DATA and for the people who work here.
For more than 25 years, NTT DATA Services have focused on impacting the core of your business operations with industry-leading outsourcing services and automation. With our industry-specific platforms, we deliver continuous value addition, and innovation that will improve your business outcomes. Outsourcing is not just a method of gaining a one-time cost advantage, but an effective strategy for gaining and maintaining competitive advantages when executed as part of an overall sourcing strategy.
NTT DATA's Client is seeking a Portfolio Manager – MES & Digital Manufacturing
Experience: 12+ Years Location: Remote/Hybrid (Travel as Required) Project Overview NTT DATA's Client is seeking an experienced Portfolio Manager to lead a portfolio of strategic Manufacturing Execution System (MES) and Digital Manufacturing initiatives within the Life Sciences industry. This role is responsible for managing multiple programs and projects across manufacturing sites, ensuring successful delivery of digital transformation initiatives that improve manufacturing efficiency, product quality, regulatory compliance, and operational excellence. The ideal candidate will possess a strong background in pharmaceutical or life sciences manufacturing, digital manufacturing technologies, MES implementations, and enterprise program management. This role requires close collaboration with business stakeholders, manufacturing operations, quality, IT, validation, and external implementation partners to deliver scalable and compliant manufacturing solutions.
Key Responsibilities
Portfolio Management Manage and govern a portfolio of MES and Digital Manufacturing programs across multiple manufacturing sites. Define portfolio strategy, roadmap, priorities, budgets, and resource allocation. Monitor portfolio health, delivery milestones, risks, dependencies, and financial performance. Establish governance frameworks, executive reporting, and KPI dashboards. Ensure alignment of manufacturing digital initiatives with organizational business objectives.
Program & Project Leadership
Lead cross-functional teams responsible for MES implementation, upgrades, and digital transformation initiatives. Manage multiple concurrent projects from planning through deployment and hypercare. Drive project planning, scheduling, budgeting, vendor management, and executive communications. Resolve cross-program risks, issues, and resource conflicts.
Business & Stakeholder Management
Partner with Manufacturing, Quality, Engineering, Supply Chain, Validation, and IT leadership. Facilitate executive steering committee meetings and provide regular portfolio status updates. Build strong relationships with site leadership and global business stakeholders. Drive organizational change management and user adoption initiatives.
Digital Manufacturing Leadership
Lead initiatives involving Manufacturing Execution Systems (MES), Manufacturing Operations Management (MOM), and Smart Manufacturing. Support manufacturing digitalization initiatives including automation, paperless manufacturing, electronic batch records, manufacturing analytics, and Industry 4.0 capabilities. Promote standardization and harmonization of manufacturing processes across global sites.
Compliance & Quality
Ensure solutions comply with Life Sciences regulatory requirements including: GxP FDA 21 CFR Part 11 EU Annex 11 GAMP 5 Computer Software Assurance (CSA) Support validation planning and ensure regulatory readiness for manufacturing systems.
Financial & Vendor Management
Manage portfolio budgets, forecasts, and financial reporting. Oversee system integrators, implementation partners, and software vendors. Track value realization and return on investment (ROI) across manufacturing initiatives.
Required Qualifications
Bachelor's degree in Engineering, Information Technology, Computer Science, Life Sciences, or a related discipline. 12+ years of IT and Digital Transformation experience. 5+ years managing enterprise portfolios or large programs focused on MES and Digital Manufacturing. 5+ years of proven experience delivering multiple global manufacturing technology initiatives. 5+ years of strong experience within the Life Sciences, Pharmaceutical, Biotechnology, or Medical Devices industry. 5+ years of experience managing global cross-functional teams and complex stakeholder environments.
Required Technical & Functional Expertise
Manufacturing Execution Systems (MES) Digital Manufacturing & Manufacturing Operations Management (MOM) Smart Manufacturing / Industry 4.0 Electronic Batch Records (EBR) Manufacturing Process Digitalization Manufacturing Systems Integration Program & Portfolio Management Agile and Waterfall delivery methodologies Vendor & Budget Management Executive Stakeholder Management Risk and Governance Management Preferred Experience Experience with one or more of the following platforms: Werum Client-X Rockwell PharmaSuite Siemens Opcenter Execution Pharma Emerson Syncade Körber Client-X SAP Manufacturing Integration & Intelligence (SAP MII) SAP Digital Manufacturing Aveva Manufacturing Execution Systems Preferred Certifications PMP or PgMP PMI Portfolio Management Professional (PfMP) SAFe Program Consultant (SPC) or SAFe Agilist ITIL Foundation Lean Six Sigma Green Belt or Black Belt Key Skills Portfolio Management Program Management MES Digital Manufacturing Manufacturing Operations Management (MOM) Life Sciences Pharmaceutical Manufacturing GxP FDA 21 CFR Part 11 GAMP 5 CSA Electronic Batch Records (EBR) Industry 4.0 Smart Manufacturing Executive Stakeholder Management Budget & Financial Management Risk & Governance Vendor Management Agile Delivery Manufacturing Digital Transformation About NTT DATA Services:
NTT DATA Services is a recognized leader in IT and business services, including cloud, data and applications, headquartered in Texas. As part of NTT DATA, a $30 billion trusted global innovator with a combined global reach of over 80 countries, we help clients transform through business and technology consulting, industry and digital solutions, applications development and management, managed edge-to-cloud infrastructure services, BPO, systems integration and global data centers. We are committed to our clients' long-term success. Visit nttdata.com or LinkedIn to learn more.
NTT DATA Services is an equal opportunity employer and considers all applicants without regarding to race, color, religion, citizenship, national origin, ancestry, age, sex, sexual orientation, gender identity, genetic information, physical or mental disability, veteran or marital status, or any other characteristic protected by law. We are committed to creating a diverse and inclusive environment for all employees. If you need assistance or an accommodation due to a disability, please inform your recruiter so that we may connect you with the appropriate team.
Where required by law, NTT DATA provides a reasonable range of compensation for specific roles. The starting hourly range for this remote role is ($x - x/hourly ). This range reflects the minimum and maximum target compensation for the position across all US locations. Actual compensation will depend on several factors, including the candidate's actual work location, relevant experience, technical skills, and other qualifications.
This position is eligible for company benefits that will depend on the nature of the role offered. Company benefits may include medical, dental, and vision insurance, flexible spending or health savings account, life, and AD&D insurance, short-and long-term disability coverage, paid time off, employee assistance, participation in a 401k program with company match, and additional voluntary or legally required benefits.
Not the right fit? Search for Portfolio Manager jobs in Ottawa, Ontario, Canada
About NTT DATA Services
NTT DATA, Inc. is a trusted global innovator of business and technology services. We're committed to helping clients innovate, optimize and transform for long-term success. Our R&D investments help organizations and society move confidently and sustainably into the digital future. As a Global Top Employer, we have diverse experts in more than 50 countries and a robust partner ecosystem of established and start-up companies. Our services include business and technology consulting, data and artificial intelligence, industry solutions, as well as the development, implementation and management of applications, infrastructure, and connectivity.
Similar Jobs
Portfolio Manager - MES & Digital Manufacturing
Top Benefits
About the role
At NTT DATA, we know that with the right people on board, anything is possible. The quality, integrity, and commitment of our employees have been key factors in our company's growth and market presence. By hiring the best people and helping them grow both professionally and personally, we ensure a bright future for NTT DATA and for the people who work here.
For more than 25 years, NTT DATA Services have focused on impacting the core of your business operations with industry-leading outsourcing services and automation. With our industry-specific platforms, we deliver continuous value addition, and innovation that will improve your business outcomes. Outsourcing is not just a method of gaining a one-time cost advantage, but an effective strategy for gaining and maintaining competitive advantages when executed as part of an overall sourcing strategy.
NTT DATA's Client is seeking a Portfolio Manager – MES & Digital Manufacturing
Experience: 12+ Years Location: Remote/Hybrid (Travel as Required) Project Overview NTT DATA's Client is seeking an experienced Portfolio Manager to lead a portfolio of strategic Manufacturing Execution System (MES) and Digital Manufacturing initiatives within the Life Sciences industry. This role is responsible for managing multiple programs and projects across manufacturing sites, ensuring successful delivery of digital transformation initiatives that improve manufacturing efficiency, product quality, regulatory compliance, and operational excellence. The ideal candidate will possess a strong background in pharmaceutical or life sciences manufacturing, digital manufacturing technologies, MES implementations, and enterprise program management. This role requires close collaboration with business stakeholders, manufacturing operations, quality, IT, validation, and external implementation partners to deliver scalable and compliant manufacturing solutions.
Key Responsibilities
Portfolio Management Manage and govern a portfolio of MES and Digital Manufacturing programs across multiple manufacturing sites. Define portfolio strategy, roadmap, priorities, budgets, and resource allocation. Monitor portfolio health, delivery milestones, risks, dependencies, and financial performance. Establish governance frameworks, executive reporting, and KPI dashboards. Ensure alignment of manufacturing digital initiatives with organizational business objectives.
Program & Project Leadership
Lead cross-functional teams responsible for MES implementation, upgrades, and digital transformation initiatives. Manage multiple concurrent projects from planning through deployment and hypercare. Drive project planning, scheduling, budgeting, vendor management, and executive communications. Resolve cross-program risks, issues, and resource conflicts.
Business & Stakeholder Management
Partner with Manufacturing, Quality, Engineering, Supply Chain, Validation, and IT leadership. Facilitate executive steering committee meetings and provide regular portfolio status updates. Build strong relationships with site leadership and global business stakeholders. Drive organizational change management and user adoption initiatives.
Digital Manufacturing Leadership
Lead initiatives involving Manufacturing Execution Systems (MES), Manufacturing Operations Management (MOM), and Smart Manufacturing. Support manufacturing digitalization initiatives including automation, paperless manufacturing, electronic batch records, manufacturing analytics, and Industry 4.0 capabilities. Promote standardization and harmonization of manufacturing processes across global sites.
Compliance & Quality
Ensure solutions comply with Life Sciences regulatory requirements including: GxP FDA 21 CFR Part 11 EU Annex 11 GAMP 5 Computer Software Assurance (CSA) Support validation planning and ensure regulatory readiness for manufacturing systems.
Financial & Vendor Management
Manage portfolio budgets, forecasts, and financial reporting. Oversee system integrators, implementation partners, and software vendors. Track value realization and return on investment (ROI) across manufacturing initiatives.
Required Qualifications
Bachelor's degree in Engineering, Information Technology, Computer Science, Life Sciences, or a related discipline. 12+ years of IT and Digital Transformation experience. 5+ years managing enterprise portfolios or large programs focused on MES and Digital Manufacturing. 5+ years of proven experience delivering multiple global manufacturing technology initiatives. 5+ years of strong experience within the Life Sciences, Pharmaceutical, Biotechnology, or Medical Devices industry. 5+ years of experience managing global cross-functional teams and complex stakeholder environments.
Required Technical & Functional Expertise
Manufacturing Execution Systems (MES) Digital Manufacturing & Manufacturing Operations Management (MOM) Smart Manufacturing / Industry 4.0 Electronic Batch Records (EBR) Manufacturing Process Digitalization Manufacturing Systems Integration Program & Portfolio Management Agile and Waterfall delivery methodologies Vendor & Budget Management Executive Stakeholder Management Risk and Governance Management Preferred Experience Experience with one or more of the following platforms: Werum Client-X Rockwell PharmaSuite Siemens Opcenter Execution Pharma Emerson Syncade Körber Client-X SAP Manufacturing Integration & Intelligence (SAP MII) SAP Digital Manufacturing Aveva Manufacturing Execution Systems Preferred Certifications PMP or PgMP PMI Portfolio Management Professional (PfMP) SAFe Program Consultant (SPC) or SAFe Agilist ITIL Foundation Lean Six Sigma Green Belt or Black Belt Key Skills Portfolio Management Program Management MES Digital Manufacturing Manufacturing Operations Management (MOM) Life Sciences Pharmaceutical Manufacturing GxP FDA 21 CFR Part 11 GAMP 5 CSA Electronic Batch Records (EBR) Industry 4.0 Smart Manufacturing Executive Stakeholder Management Budget & Financial Management Risk & Governance Vendor Management Agile Delivery Manufacturing Digital Transformation About NTT DATA Services:
NTT DATA Services is a recognized leader in IT and business services, including cloud, data and applications, headquartered in Texas. As part of NTT DATA, a $30 billion trusted global innovator with a combined global reach of over 80 countries, we help clients transform through business and technology consulting, industry and digital solutions, applications development and management, managed edge-to-cloud infrastructure services, BPO, systems integration and global data centers. We are committed to our clients' long-term success. Visit nttdata.com or LinkedIn to learn more.
NTT DATA Services is an equal opportunity employer and considers all applicants without regarding to race, color, religion, citizenship, national origin, ancestry, age, sex, sexual orientation, gender identity, genetic information, physical or mental disability, veteran or marital status, or any other characteristic protected by law. We are committed to creating a diverse and inclusive environment for all employees. If you need assistance or an accommodation due to a disability, please inform your recruiter so that we may connect you with the appropriate team.
Where required by law, NTT DATA provides a reasonable range of compensation for specific roles. The starting hourly range for this remote role is ($x - x/hourly ). This range reflects the minimum and maximum target compensation for the position across all US locations. Actual compensation will depend on several factors, including the candidate's actual work location, relevant experience, technical skills, and other qualifications.
This position is eligible for company benefits that will depend on the nature of the role offered. Company benefits may include medical, dental, and vision insurance, flexible spending or health savings account, life, and AD&D insurance, short-and long-term disability coverage, paid time off, employee assistance, participation in a 401k program with company match, and additional voluntary or legally required benefits.
Not the right fit? Search for Portfolio Manager jobs in Ottawa, Ontario, Canada
About NTT DATA Services
NTT DATA, Inc. is a trusted global innovator of business and technology services. We're committed to helping clients innovate, optimize and transform for long-term success. Our R&D investments help organizations and society move confidently and sustainably into the digital future. As a Global Top Employer, we have diverse experts in more than 50 countries and a robust partner ecosystem of established and start-up companies. Our services include business and technology consulting, data and artificial intelligence, industry solutions, as well as the development, implementation and management of applications, infrastructure, and connectivity.