As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease.

We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research.

The Brain Ageing and Neurodegeneration led by Prof. Marc Aurel Busche, is looking for a Research / Lab Assistant.

Join our community and help shape the future of biomedicine.

Your position

We are looking for a motivated and technically skilled Research / Lab Assistant (60–100%) to join a newly funded project investigating how tau pathology disrupts neural circuit function during the early stages of Alzheimer's disease.

The project combines mouse behaviour, chronic multi-region electrophysiological recordings (Neuropixels), viral approaches, and analysis of large-scale neural population activity to study how pathological changes in neural activity emerge and contribute to cognitive impairment.

Your Responsibilities

Perform and support experimental procedures in mice, including stereotaxic surgeries, behavioural training and testing and chronic in vivo electrophysiological recordings Support histological processing and sample preparation for ex vivo experiments Support the monitoring of animals before, during, and after experimental procedures

Your profile

Valid certification to perform animal experiments in Switzerland (LTK1 or equivalent qualification) At least 2 years of hands-on experience with in vivo experiments in rodents, gained through a technical apprenticeship, veterinary technician training, or a Bachelor's/Master's degree in a relevant field Experience working with rodents in a research environment, including animal handling, welfare monitoring, and experimental documentation Careful, organised, and reliable working style with the ability to work independently Good communication skills in English

Preferred

Experience with stereotaxic surgery in rodents Experience with in vivo electrophysiology and/or neural recording techniques Experience with behavioural neuroscience experiments Ability to communicate in German is an advantage

We offer you

A 2-year fixed-term position (60–100%) Training in advanced in vivo neuroscience techniques, including chronic Neuropixels recordings Opportunity to contribute to establishing new experimental workflows and longitudinal studies An international and collaborative research environment

Start date: As soon as possible or by arrangement

Application

Please submit a CV, short motivation letter, and contact details of 2 references.

Apply

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