Scientist II, Immunology & Respiratory

Job summary

The Scientist II will support disease positioning efforts by performing quantitative digital image analysis of protein and mRNA expression in human tissues. They will also manage tissue resources and assist in the development and application of advanced molecular histopathology techniques.

Job details

Description Boehringer Ingelheim is currently seeking a talented and innovative Scientist II to join our Immunology and Respiratory Diseases Research Department located at our Ridgefield, CT facility. The purpose of this position is to support disease positioning efforts using quantitative digital image analysis of protein and mRNA expression in human tissues to enhance our understanding of the biology of therapeutically relevant proteins and pathways in health and disease. This will involve the application of multiplex fluorescence immunohistochemistry and mRNA in situ hybridization, support for spatial transcriptomics and proteomics, the development and application of image analysis algorithms, and the management of tissue resources. As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies´ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim´s high regard for our employees.Duties & Responsibilities Initiates, designs, interprets accurately, and completes routine procedures in an independent and efficient manner, with minimal supervision; demonstrates technical ability to assist in the design and execution of non-routine experiments with supervision. Independently operates and is responsible for lab equipment; troubleshoots effectively. Applies basic scientific principles with minimal guidance; performs literature searches and extracts relevant information from published protocols. Obtains, optimizes, and validates antibodies for research activities; procures and validates appropriate controls. Assists with the incorporation of new technologies or best practices in area of molecular histopathology and image analysis. Effectively communicates and defends own work, orally and in writing, in the context of the team goals at meetings. Reports and treats data with a high level of integrity and ethics. Complies with applicable regulations, performing all work in a safe manner; maintains proper records in accordance with SOPs and policies. Requirements Bachelors Degree with 3+ years experience in related scientific discipline or Masters Degree in related scientific discipline or equivalent experience in related field Industry experience is desirable Laboratory expertise developing, validating, and running immunohistochemistry, mRNA in situ hybridization, as well as multiplexing immunohistochemistry and in situ hybridization assays Knowledge of quantitative image analysis techniques and software, and AI-based image analysis Familiarity with immunology, auto-immune and auto-inflammatory diseases is desirable Strong inter-personal skills and a proven track record of collaboration and working effectively in matrixed teams An ability to communicate effectively both orally and in writing in an inter-disciplinary environment Other desirable attributes include superior problem-solving skills, strong motivation, and high levels of organization. Ensure the safety of the laboratory, quality control and quality assurance standards for the histology laboratory Eligibility Requirements: Must be legally authorized to work in the United States without restriction. Must be willing to take a drug test and post-offer physical (if required). Must be 18 years of age or older. Compensation Data The base salary range for Scientist II is $74,800.00 to $112,200.00. The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please click here.

What you’ll do

The Scientist II will support disease positioning efforts by performing quantitative digital image analysis of protein and mRNA expression in human tissues. They will also manage tissue resources and assist in the development and application of advanced molecular histopathology techniques.

Requirements

Candidates must hold a Bachelor's degree with at least 3 years of relevant experience or a Master's degree in a scientific discipline. Proficiency in immunohistochemistry, in situ hybridization, and quantitative image analysis software is required.

Benefits

• Competitive compensation • Discretionary bonus • Relocation assistance

Listed skills

• Control · Preferred
• Software · Preferred
• Problem solving · Preferred
• analysis · Preferred
• Collaboration · Preferred
• Positioning · Preferred
• Health · Preferred
• Execution · Preferred
• management · Preferred
• Assurance · Preferred
• Development · Preferred
• discipline · Preferred

Other relevant skills

Identified from the job description. Confirm important requirements above.

• Immunohistochemistry
• mRNA in situ hybridization
• Multiplex fluorescence
• Digital image analysis
• Spatial transcriptomics
• Spatial proteomics
• Molecular histopathology
• Algorithm development
• Antibody validation
• Immunology
• Auto-immune diseases
• Auto-inflammatory diseases
• Data integrity
• Laboratory safety
• Scientific communication
• Matrixed team collaboration
• In Situ Hybridization
• Laboratory Equipment
• Proteomics
• Ethical Standards And Conduct
• Research
• Artificial Intelligence
• Algorithms
• Antibodies
• Biochemical Assays
• Biology
• Management
• Communication
• Image Analysis
• Multiplexing
• Digital Image Processing
• Histology
• Histopathology
• Innovation
• Problem Solving
• MRNAs
• Respiratory Diseases
• Quality Assurance
• Writing
• Quality Control

Job areas

• Science & Research
• Healthcare
• Technology
• Immunology Specialist
• Molecular Biologist
• Biologists, Botanists, Zoologists and Related Professionals
• Molecular and Cellular Biologists
• Biological Scientists, All Other