Senior Clinical Research Scientist

Job summary

Lead the scientific and clinical execution of global oncology studies, including study design, medical monitoring, safety oversight, data review, and collaboration with investigators and cross-functional teams. Contribute to regulatory submissions, clinical study reports, publications, and study training, while mentoring junior clinical scientists as needed.

Job details

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise. As the world’s largest FSP organization, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide. Senior Clinical Research Scientist (Oncology) 📍 Location: United States or Canada (Remote) ✈️ Travel: Up to 15% (including occasional international travel) Are you an experienced Clinical Research Scientist with a passion for advancing oncology therapies? We are seeking a Senior Clinical Research Scientist to provide scientific leadership and clinical oversight across global oncology clinical trials. This is an exciting opportunity to partner with cross-functional teams and play a critical role in study design, execution, data interpretation, and regulatory deliverables that help bring innovative treatments to patients. What You'll Do As a key scientific leader, you will drive the clinical and scientific execution of oncology studies and serve as a trusted partner to internal and external stakeholders. Key responsibilities include: Lead or support one or more clinical studies, depending on size and complexity. Serve as the primary scientific point of contact for investigators, study teams, IRBs, and other stakeholders. Contribute to protocol design, endpoint development, and study strategy in collaboration with Clinical Development. Lead medical monitoring activities, including Medical Monitoring Plan development and SAE review oversight. Support Safety Adjudication Committees (SAC), Data Monitoring Committees (DMC), and adjudication committees. Collaborate on the development and review of protocols, amendments, informed consent forms, and study-specific documentation. Author protocol clarification letters and contribute to scientific communications. Provide scientific oversight for clinical data review, safety monitoring, data management activities, and external data sources. Monitor laboratory, imaging, and biomarker data for safety signals and clinically significant findings. Serve as the scientific lead on Clinical Trial Teams and support investigator meetings through presentations and study training. Participate in database lock activities, clinical study reports (CSR), regulatory submissions, and publication planning. Review and classify protocol deviations and contribute to CSR documentation. Partner with medical writing, study management, and operational teams to ensure high-quality study execution and deliverables. Mentor and support junior Clinical Scientists as needed. What We're Looking For Required Qualifications BS/BA in Life Sciences with 7+ years of clinical research experience, OR MS or PhD in Life Sciences with 5+ years of clinical research experience, OR Significant clinical development experience (11+ years) in lieu of a Life Sciences degree. Experience & Skills ✅ Minimum 2 years of experience as a lead Clinical Scientist within pharmaceutical, biotechnology, or clinical drug development environments. ✅ Oncology clinical trial experience required. ✅ Medical monitoring experience required. ✅ Strong understanding of: Clinical trial design and execution Oncology drug development Clinical data review and interpretation Safety monitoring and regulatory requirements ✅ Advanced proficiency in: Microsoft Excel PowerPoint Clinical data analysis and presentation ✅ Exceptional written and verbal communication skills with the ability to collaborate across global, cross-functional teams. Why Apply? Contribute to innovative oncology programs that have the potential to change patients' lives. Take on a highly visible scientific leadership role within clinical development. Collaborate with experienced clinical, medical, regulatory, and operational teams. Work remotely from anywhere in the United States or Canada. Be part of a dynamic environment where scientific expertise directly influences study success. Employment with ICON is contingent upon having the legal right to work in the country where the role is based. Rewards & Benefits ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development. Benefits may include: Competitive base salary and performance related incentives Health and wellbeing programmes including medical, dental, and vision coverage where applicable Retirement and pension plans Life assurance and disability coverage Employee assistance programmes and wellbeing resources Learning and development opportunities through structured training and career pathways Benefits may vary depending on role and location. Visit our careers site to read more about the benefits ICON offers. Inclusion and Accessibility ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported. If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

What you’ll do

Lead the scientific and clinical execution of global oncology studies, including study design, medical monitoring, safety oversight, data review, and collaboration with investigators and cross-functional teams. Contribute to regulatory submissions, clinical study reports, publications, and study training, while mentoring junior clinical scientists as needed.

Requirements

Requires a life sciences bachelor's degree with at least 7 years of clinical research experience, a master's or PhD with at least 5 years, or 11+ years of clinical development experience in lieu of a degree. Candidates must have at least 2 years as a lead Clinical Scientist, oncology trial and medical monitoring experience, strong clinical and regulatory expertise, advanced Excel and PowerPoint proficiency, and excellent communication skills.

Benefits

• Competitive Base Salary
• Performance-Related Incentives
• Medical Coverage
• Dental Coverage
• Vision Coverage
• Retirement and Pension Plans
• Life Assurance
• Disability Coverage
• Employee Assistance Programs
• Wellbeing Resources
• Learning and Development Opportunities

Listed skills

• safety monitoring · Preferred
• Microsoft Excel · Preferred
• Cross-Functional Collaboration · Preferred

Other relevant skills

Identified from the job description. Confirm important requirements above.

• Clinical Research
• Oncology Clinical Trials
• Clinical Trial Design
• Clinical Study Execution
• Medical Monitoring
• Safety Monitoring
• Clinical Data Review
• Data Interpretation
• Protocol Development
• Endpoint Development
• Regulatory Submissions
• Clinical Study Reports
• Microsoft Excel
• Microsoft PowerPoint
• Scientific Communication
• Cross-Functional Collaboration

Job areas

• Healthcare
• Science & Research
• Management & Leadership

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