Principal Clinical Scientist

Job summary

Design and review clinical trial protocols and audit trial results to ensure datasets and interpretations are accurate, scientifically sound, and aligned with regulatory standards. Evaluate AI-generated clinical analyses and provide structured expert feedback to improve AI reasoning about clinical data, endpoints, and outcomes.

Job details

Principal Clinical Scientist (AI Training) About The Role What if your decades of clinical trial expertise could directly shape how AI understands and evaluates biomedical evidence for millions of researchers, clinicians, and patients worldwide? We're looking for a Principal Clinical Scientist to bring senior-level authority in clinical trial design and regulatory-grade data interpretation into cutting-edge AI research workflows. Your expertise will help ensure that the AI systems influencing the future of clinical and biomedical science are built on rigorous, accurate, and regulation-ready foundations. This is a fully remote, flexible contract role. No prior AI experience needed — just deep command of clinical trial methodology and regulatory science. Organization: Alignerr Type: Hourly Contract Location: Remote Commitment: 10–40 hours/week What You'll Do Design and critically review clinical trial protocols that generate high-quality, regulator-ready datasets for AI training and evaluation Interpret and audit clinical trial results to verify accuracy, consistency, and alignment with regulatory standards Evaluate AI-generated clinical analyses for scientific soundness and regulatory appropriateness Provide expert, structured feedback to improve how AI models reason about clinical trial data, endpoints, and outcomes Work independently and asynchronously — fully on your own schedule Who You Are Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies Strong grounding in clinical research methodology, biostatistics, or translational science Naturally rigorous and detail-oriented — you hold clinical data to the highest standards Clear and precise written communicator who can document scientific reasoning effectively Comfortable working independently across varied clinical topics and therapeutic areas Nice to Have Prior experience with data annotation, data quality assurance, or evaluation frameworks Familiarity with AI tools or model evaluation workflows as an end user Background spanning multiple therapeutic areas or regulatory jurisdictions Experience in medical writing, evidence synthesis, or systematic review Why Join Us Work directly on frontier AI systems shaping the future of clinical and biomedical research Fully remote and flexible — work when and where it suits you Freelance autonomy with the structure of meaningful, high-impact scientific work Influence how AI understands, evaluates, and reasons about real-world clinical evidence at scale Collaborate with leading AI research teams and labs on genuinely novel challenges Potential for ongoing work and contract extension as new projects launch

What you’ll do

Design and review clinical trial protocols and audit trial results to ensure datasets and interpretations are accurate, scientifically sound, and aligned with regulatory standards. Evaluate AI-generated clinical analyses and provide structured expert feedback to improve AI reasoning about clinical data, endpoints, and outcomes.

Requirements

Requires senior-level, hands-on experience designing clinical trial protocols for regulatory submission and deep expertise interpreting clinical data for agencies such as the FDA or EMA. Candidates should have strong grounding in clinical research methodology, biostatistics, or translational science, along with rigorous attention to detail and clear written communication.

Benefits

• Flexible Schedule
• Remote Work
• Freelance Autonomy
• Potential Contract Extension

Listed skills

• Évaluation · Preferred
• Organization · Preferred
• Training · Preferred
• Quality assurance · Preferred
• Attention to detail · Preferred
• Detail-oriented · Preferred
• Teams · Preferred
• Assurance · Preferred
• Accuracy · Preferred
• future · Preferred
• Audit · Preferred
• Flexible · Preferred

Other relevant skills

Identified from the job description. Confirm important requirements above.

• Clinical Trial Design
• Clinical Trial Protocol Development
• Regulatory Science
• Clinical Data Interpretation
• Clinical Data Auditing
• Biostatistics
• Clinical Research Methodology
• AI Model Evaluation
• Scientific Review
• Data Quality Assurance
• Structured Feedback
• Medical Writing
• Evidence Synthesis
• Systematic Review
• Scientific Communication

Job areas

• Healthcare
• Science & Research
• Technology
• Data & Analytics

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