McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care. What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you. Summary The Principal, Digital Transformation serves as the senior technology leader and strategic IT partner for McKesson’s Ontada business. This role is responsible for shaping technology strategy, driving digital transformation initiatives, overseeing end-to-end solution delivery, and ensuring operational excellence across business-critical platforms. As a senior individual contributor, the role influences enterprise-wide outcomes through executive partnership, strategic leadership, and cross-functional collaboration without direct people management responsibilities.

What You'll Do

Serve as the primary IT strategy partner to senior business leaders within Ontada. Develop and maintain multi-year technology strategies, roadmaps, and investment plans aligned to business objectives Provide end-to-end accountability for technology delivery across multiple initiatives, programs, and business domains Drive successful execution of digital transformation initiatives that improve customer outcomes and business performance Ensure operational health, scalability, reliability, security, and compliance of critical technology platforms Act as a senior escalation point for complex business, technology, and operational challenges Partner with enterprise architecture, engineering, delivery, and operations teams to align strategic direction and execution Promote adoption of modern technologies, including AI, machine learning, automation, cloud platforms, and advanced analytics Influence enterprise technology direction through leadership, stakeholder engagement, and strategic recommendations Identify risks, opportunities, and innovation initiatives that support long-term business growth and transformation goals

What You Bring

Extensive experience partnering with executive and senior business leaders to define and execute IT strategies Proven success leading enterprise-scale digital transformation and technology modernization initiatives Strong understanding of cloud-native platforms, data and analytics, APIs, automation, and AI/ML technologies Experience driving technology outcomes and influencing stakeholders without formal reporting authority Knowledge of enterprise architecture principles, integration patterns, scalability, reliability, and security practices Experience operating within regulated industries, with healthcare or life sciences experience considered a strong asset Strong strategic thinking, analytical, and problem-solving capabilities Excellent executive communication and stakeholder management skills Ability to navigate ambiguity, balance competing priorities, and drive alignment across complex organizations Demonstrated ability to lead change, foster innovation, and deliver measurable business value.

Minimum Requirements

Bachelor’s degree or equivalent experience required and typically requires 12+ years of relevant experience in technology leadership, digital transformation, enterprise systems, or related disciplines. Less years required if possessing relevant Master’s or Doctorate qualifications.

Preferred Skills & Experience

Experience with AI, machine learning, automation, and emerging technologies applied to business transformation Experience leading technology initiatives within regulated healthcare, life sciences, or similar highly regulated environments Strong understanding of regulatory compliance, risk management, and security frameworks Experience supporting customer-facing digital platforms and driving technology-enabled business outcomes Experience working across enterprise technology functions including architecture, engineering, operations, and product teams Advanced degree in Technology, Engineering, Business, or a related field preferred

Work Model / Physical Requirements We are Flex and Connect with 2 days a week in office. We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$149,600 - $199,500 McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates. McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page. McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted. Join us at McKesson!