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Xenon Pharmaceuticals Inc.

Verified Job Source

A neuroscience-focused biopharmaceutical company

Burnaby, BC

Biotechnology Research
201–500 people

About

Xenon Pharmaceuticals is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. Our lead molecule, azetukalner, is a novel, potent, selective Kv7 potassium channel opener in Phase 3 clinical trials for the treatment of epilepsy, major depressive disorder (MDD) and bipolar depression (BPD). We are also advancing an early-stage portfolio of multiple promising potassium and sodium channel modulators, including Kv7 and Nav1.7 programs in Phase 1 development for the potential treatment of pain. We have offices in Vancouver, British Columbia, and Boston, Massachusetts.

Open positions

Clinical Trial Associate 1 or 2

Hybrid · Burnaby

The Clinical Trial Associate supports the clinical operations team by managing project-specific tasks, tracking clinical trial progress, and maintaining essential study documentation. They collaborate with CROs and vendors to ensure efficient trial conduct, including document review, site activation support, and quality oversight of the electronic trial master file.

Associate Director, CMC, Drug Product

Hybrid · Burnaby

The Associate Director will lead non-clinical and early-phase clinical formulation and process development activities for small molecule drug products. They will manage CDMO relationships, oversee manufacturing activities, and ensure CMC documentation meets regulatory requirements for global filings.

Associate Director, Quality Control

Hybrid · Burnaby

The Associate Director will lead quality control activities for clinical and commercial drug substance and drug product programs, ensuring compliance with ICH and cGMP requirements. Responsibilities include managing stability programs, overseeing analytical testing, leading investigations for OOS/OOT results, and managing relationships with external testing laboratories.

Research Associate 1, Biology (In Vivo) (14 Month Contract)

On-site · Burnaby

The Research Associate will provide technical in vivo support for preclinical drug discovery projects, including conducting pharmacology experiments and ensuring animal welfare. They are responsible for administering test compounds, collecting samples, and maintaining detailed experimental records in an electronic lab notebook.

Senior Manager, Trial Operations

Hybrid · Burnaby

The Senior Manager, Trial Operations is responsible for the strategic and hands-on delivery of Phase 3 clinical trials from start-up through closeout. This role involves managing cross-functional teams, overseeing external vendors, and ensuring high-quality study execution within budget and timeline constraints.

Senior Manager/Associate Director, Quality Control

Hybrid · Burnaby

The Senior Manager/Associate Director will lead quality control activities for clinical and commercial drug substance and drug product programs, ensuring compliance with ICH and cGMP requirements. Responsibilities include managing analytical results, stability programs, reference standards, and leading investigations for out-of-specification or out-of-trend observations.

Senior Project Manager/Associate Director, Discovery Project Management

Hybrid · Burnaby

The Senior Project Manager will manage Discovery-stage programs, including coordinating cross-functional teams, tracking timelines, and managing budgets. They will also oversee external Contract Research Organizations (CROs) and facilitate the progression of compounds through preclinical development.

Animal Care Technician

On-site · Burnaby

The Animal Care Technician will perform routine husbandry duties, monitor animal health, and maintain facility cleanliness in accordance with CCAC guidelines. They will also assist with technical procedures, maintain accurate health records, and manage inventory for the resource facility.

Discovery Operations Coordinator

On-site · Burnaby

Provides administrative and operational support to the Discovery Program Management team, including calendar management and travel coordination. Manages the ingestion and organization of scientific data from external contractors into enterprise systems and maintains laboratory inventory.

Clinical Scientist 2 or 3, Clinical Development

Hybrid · Burnaby

The Clinical Scientist provides scientific leadership in the design, execution, and analysis of clinical trials for neuroscience programs. They are responsible for drafting regulatory documents and collaborating cross-functionally to ensure study rigor and alignment with regulatory expectations.

Director/Senior Director, CMC, Drug Product Manufacturing (Late Stage/Commercial)

Hybrid · Burnaby

The Director, CMC, Drug Product oversees late-stage process development, validation, and commercial manufacturing of drug products through external partners. They are responsible for ensuring regulatory compliance, managing CDMO relationships, and providing strategic oversight for CMC documentation and submissions.

Manager, Internal Communications

Hybrid · Burnaby

Develop and execute internal communication strategies and corporate engagement initiatives to foster company culture and mission. Lead the planning and execution of large-scale corporate events and executive offsites while managing vendor relationships and budgets.

Senior Manager, Data Management

Hybrid · Burnaby

Lead and manage data management activities for clinical trials across all phases, including the design of databases and CRF development. Oversee external data management vendors and ensure compliance with ICH/GCP guidelines and regulatory requirements.

Clinical Trial Associate 1

Hybrid

***Who We Are:*** Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. ***What We Do:*** We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically v…

Executive Director, Total Rewards

Hybrid · Burnaby

Lead the design and execution of competitive total rewards strategies, including base salary, bonuses, equity, and benefits for the US and Canada. Collaborate with executive leadership and the Board to align compensation programs with business objectives and regulatory requirements.

Director, CMC, Drug Product

Hybrid

Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potass…